Child Stunting is Associated with Low Circulating Essential Amino Acids
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چکیده
منابع مشابه
Child Stunting is Associated with Low Circulating Essential Amino Acids.
BACKGROUND Stunting affects about one-quarter of children under five worldwide. The pathogenesis of stunting is poorly understood. Nutritional interventions have had only modest effects in reducing stunting. We hypothesized that insufficiency in essential amino acids may be limiting the linear growth of children. METHODS We used a targeted metabolomics approach to measure serum amino acids, g...
متن کاملLow Circulating Amino Acids and Protein Quality: An Interesting Piece in the Puzzle of Early Childhood Stunting
We commend Semba et al. (2016) for examining child stunting in the context of protein and amino acids, which, beyond supplying essential nitrogen for protein synthesis, are involved in regulation of linear growth, an issue that has not been addressed sufficiently. The authors reported significant associations between low levels of serum amino acids and stunting in a cross-sectional study of you...
متن کاملThe essential amino-acids.
Osborne, T. B. and Mendel, L. B. (1914). Pearson, H . Y. and Smith, J. A. B. (1943). Kittenberg, D. and Poster, G. L. (1940). Robei-tson, E. C. and Doyle, 31. E. (1936). Roche, A. (1934, 1 ) . Bull. SOC. Chim. biol., Paris, 16, 270. Roche, A. (1934, 2) . S h n d . Arch. Physiol. 69, 75. Rose, W. C. (1938). Phpiol. Rev. 18, 109. Rose, W. C., Haines, W. J. and Johnson, J. E. (1942). Rose, 1%’. C....
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OBJECTIVES We assessed associations between child stunting, recovery, and faltering with schooling and human capital skills in a native Amazonian society of horticulturalists-foragers (Tsimane'). METHODS We used cross-sectional data (2008) from 1262 children aged 6 to 16 years in 53 villages to assess contemporaneous associations between three height categories: stunted (height-for-age Z scor...
متن کاملMaternal Low-Protein Diet or Hypercholesterolemia Reduces Circulating Essential Amino Acids and Leads to Intrauterine Growth Restriction
OBJECTIVE We have examined maternal mechanisms for adult-onset glucose intolerance, increased adiposity, and atherosclerosis using two mouse models for intrauterine growth restriction (IUGR): maternal protein restriction and hypercholesterolemia. RESEARCH DESIGN AND METHODS For these studies, we measured the amino acid levels in dams from two mouse models for IUGR: 1) feeding C57BL/6J dams a ...
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ژورنال
عنوان ژورنال: EBioMedicine
سال: 2016
ISSN: 2352-3964
DOI: 10.1016/j.ebiom.2016.02.030